Dr. Mario (series)

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It has been requested that this article be rewritten and expanded to include more information. Reason: Include proper gameplay section and evolution from game to game, etc

Dr. Mario
Dr. Mario Logo
Japanese logo,
PAL logo since Dr. Mario & Germ Buster,
North American logo since Dr. Luigi
DrMarioLogo.png
Old international logo
First installment Dr. Mario (1990)
Latest installment Dr. Mario World (2019)
Number of installments 9
Franchise Super Mario
“Medical alert: Microscopic monsters have come out in force to take over the lab of the famous plumber turned practitioner, Dr. Mario, and you've got to set things straight. Manipulating the doctor's special vitamin capsules and making matches to obliterate the menace is Tetris-style strategic fun for one or two players!”
—Nintendo Power Issue #18, November/December 1990

The Dr. Mario series is a series of puzzle games in the Super Mario franchise. The series stars Mario's medical alter ego, Dr. Mario. It has elements similar to that of Tetris, the main concept of the game being that the player must stack multi-colored capsules (rather than blocks) in rows of a single color so that they can eradicate correspondingly colored viruses and achieve victory.

Starting with Dr. Mario Online Rx, installments in the series have been released exclusively via download.

Games

Title
Image, original release, and system Synopsis
Dr. Mario
North American box art for Dr. Mario on NES
Template:Release NES, Game Boy 		The first game in the Dr. Mario series; it was released for the NES and for the Game Boy in 1990. The game brought the basic concept of the series to the players' attention immediately, as they would start the game off having to reorganize falling vitamin capsules in order to eradicate viruses from the screen. Once all viruses has been eliminated, the player would move on to the next level. As the game progressed, each level rose in difficulty, providing more viruses for the player to eliminate and less space to maneuver the vitamin capsules in. Dr. Mario was ported and remade many times after its original release.
VS. Dr. Mario
The title screen for Vs. Dr. Mario.
Template:Release VS. System 		Dr. Mario was later released on the VS. System under the title VS. Dr. Mario. This edition of the game eliminated the Slow Mode of the game; it also made racking up points more difficult. In the original Dr. Mario, the points received for eliminating a virus would double with each one that disappeared; in this version of the game, only an additional 200 points would be rewarded for each virus that was eliminated.
Dr. Mario
Dr. Mario in its original blister pack (front view)
1993
Gamewatch Boy 		A version of the original game of the same name adapted to the Gamewatch Boy. It was manufactured by Mani and licensed by Nintendo in 1993.
Dr. Mario 64
Box art for Dr. Mario 64
Template:Release Nintendo 64 		The third installment in the Dr. Mario series, released on the Nintendo 64 in 2001. The concept from the original Dr. Mario had continued in this installment, with the only major change being a graphics update. The player still had to reorganize vitamin capsules in their respective color pattern in order to eliminate viruses. This game also featured a Story Mode. In this mode, Wario is introduced to the series. Dr. Mario and Wario must retrieve the Megavitamins that had been stolen. However, all the battles were against the computer.
Dr. Mario Online Rx
Dr. mario online rx.jpg
Template:Release Wii (WiiWare) 		Dr. Mario Online Rx (known in Europe and Australia as Dr. Mario & Germ Buster) is a game specially made for WiiWare, released in 2008. It had no story mode, unlike Dr. Mario 64, but the player can play with others online via Nintendo Wi-Fi Connection. It's also possible for the player to play as their own Mii. It actually contains two games: the original Dr. Mario, and Germ Buster (known in NTSC regions as Virus Buster), a game originally from Brain Age 2 (known in Europe as More Brain Training of Dr. Kawashima). Germ Buster is a special game that uses the motion control of the Wii Remote, to move the capsules to the Viruses. Germ Buster includes a Co-op mode in the main game self, so, if there is any other Wii Remote on, the player of that Wii Remote can play too, to help the first one. In Germ Buster the player can press on Miis too (while playing) to let then say something in a text bubble. Pressing on Viruses outside the bottle (again while playing), they'll laugh happily to the player. Players can also send demo versions of Dr. Mario Online Rx to friends, but WiiConnect24 is needed. Also, in the Demo version, the player can only play online with another friend.
Dr. Mario Express
DSiLogoDr.Mario.png
Template:Release Nintendo DSi (DSiWare) 		Dr. Mario Express (known in Europe and Australia as A Little Bit of... Dr. Mario) released on DSiWare in 2009, features gameplay that is very similar to Dr. Mario Online Rx, but the Virus Blaster minigame is not included and there is also no multiplayer feature. This was the first Super Mario DSiWare game.
Dr. Luigi
English logo for Dr. Luigi.
Template:Release Wii U (Nintendo eShop-exclusive) 		The sixth game in the series released on Nintendo eShop on Wii U, in celebration of the Year of Luigi. As the title suggests, the game features Luigi instead of Mario. Additionally, the game introduces a new mode, called Operation L, in which the player must eliminate viruses using L-capsules.
Dr. Mario: Miracle Cure
Dr. Mario: Miracle Cure Logo
Template:Release Nintendo 3DS (Nintendo eShop-exclusive) 		A game in the series for Nintendo 3DS, released exclusively on Nintendo eShop in 2015. It features a new item called "Miracle Cure" that has a random helpful effect on the playing field.
Dr. Mario World
Dr. Mario World English logo
July 9, 2019
iOS, Android 		A game in the series for mobile devices. It was initially released on July 9, 2019, and features several doctors with different abilities. It was shut down in November 2021.

Names in other languages

Language Name Meaning Notes
Japanese ドクターマリオ[?]
Dokutā Mario 		Dr. Mario
Chinese (simplified) 马力欧医生[?]
Mǎlì'ōu yīshēng 		Dr. Mario
Chinese (traditional) 瑪利歐醫生[?]
Mǎlì'ōu yīshēng 		Dr. Mario
Korean 닥터마리오[?]
Dagteomalio 		Dr. Mario

Trivia

  • The old international logo for the series, used from Dr. Mario to Dr. Mario Express in North America, stylized the "R" in "Dr." as "℞". This is in reference to a common abbreviation for a medical prescription (given that Mario is a doctor in this series), with the R crossed out being an abbreviation for Recipere (Latin for "Take thou"). Similarly, Dr. Mario Online Rx has the "Rx" stylized as "℞", but not the "R" in "Dr."
Dr. Mario coverage on other NIWA wikis:
[Edit]
Super Mario games
Platformers Super Mario series Main Super Mario Bros. (1985, NES) • Super Mario Bros.: The Lost Levels (1986, FDS) • Super Mario Bros. 2 (1988, NES) • Super Mario Bros. 3 (1988, NES) • Super Mario Land (1989, GB) • Super Mario World (1990, SNES) • Super Mario Land 2: 6 Golden Coins (1992, GB) • Super Mario 64 (1996, N64) • Super Mario Sunshine (2002, GCN) • New Super Mario Bros. (2006, DS) • Super Mario Galaxy (2007, Wii) • New Super Mario Bros. Wii (2009, Wii) • Super Mario Galaxy 2 (2010, Wii) • Super Mario 3D Land (2011, 3DS) • New Super Mario Bros. 2 (2012, 3DS) • New Super Mario Bros. U (2012, Wii U) • Super Mario 3D World (2013, Wii U) • Super Mario Maker (2015, Wii U) • Super Mario Run (2016, iOS/iPadOS/Android) • Super Mario Odyssey (2017, Switch) • Super Mario Maker 2 (2019, Switch) • Super Mario Bros. Wonder (2023, Switch)
Reissues VS. Super Mario Bros. (1986, VS) • Super Mario Bros. (1986, G&W) • All Night Nippon: Super Mario Bros. (1986, FDS) • Super Mario Bros. (1989, NGW) • Super Mario Bros. 3 (1990, NGW) • Super Mario World (1991, NGW) • Super Mario All-Stars (1993, SNES) • Super Mario All-Stars + Super Mario World (1994, SNES) • BS Super Mario USA (1996, SNES) • BS Super Mario Collection (1997, SNES) • Super Mario Bros. Deluxe (1999, GBC) • Super Mario Advance (2001, GBA) • Super Mario World: Super Mario Advance 2 (2001, GBA) • Super Mario Advance 4: Super Mario Bros. 3 (2003, GBA) • Classic NES Series (2004-2005, GBA) • Super Mario 64 DS (2004, DS) • Super Mario All-Stars Limited Edition (2010, Wii) • Super Mario Maker for Nintendo 3DS (2016, 3DS) • New Super Mario Bros. U Deluxe (2019, Switch) • Super Mario 3D All-Stars (2020, Switch) • Game & Watch: Super Mario Bros. (2020, G&W) • Super Mario 3D World + Bowser's Fury (2021, Switch)
Related games Super Mario Bros. Special (1986, computer) • Wario Land: Super Mario Land 3 (1994, GB) • Super Mario World 2: Yoshi's Island (1995, SNES) • New Super Luigi U (2013, Wii U) • Captain Toad: Treasure Tracker (2014, Wii U) • Super Mario Bros. 35 (2020, Switch) • Bowser's Fury (2021, Switch)
Canceled games Super Mario's Wacky Worlds (CD-i) • Mario Takes America (CD-i) • VB Mario Land (VB) • Super Mario 64 2 (N64DD)
Donkey Kong series Donkey Kong (1981, arcade) • Donkey Kong (1994, GB)
Mario vs. Donkey Kong series Mario vs. Donkey Kong (2004, GBA) • Mario vs. Donkey Kong 2: March of the Minis (2006, DS) • Mario vs. Donkey Kong: Minis March Again! (2009, DSiWare) • Mario vs. Donkey Kong: Mini-Land Mayhem! (2010, DS) • Mario and Donkey Kong: Minis on the Move (2013, 3DS) • Mario vs. Donkey Kong: Tipping Stars (2015, 3DS/Wii U) • Mini Mario & Friends: amiibo Challenge (2016, 3DS/Wii U)
Mario Bros. series Mario Bros. (1983, arcade) • Mario Bros. Special (1984, computer) • Punch Ball Mario Bros. (1984, computer) • Mario Clash (1995, VB)
Wrecking Crew series VS. Wrecking Crew (1984, VS) • Wrecking Crew (1985, NES) • Wrecking Crew '98 (1998, SFC)
Other Mario Bros. (1983, G&W) • Mario's Cement Factory (1983, G&W) • Mario & Wario (1993, SNES) • Hotel Mario (1994, CD-i) • Super Princess Peach (2005, DS) • Princess Peach: Showtime! (2024, Switch)
Reissues Crazy Kong (1981, arcade) • Donkey Kong (1982, G&W) • Mario Bros. Returns (1988, FDS) • Donkey Kong (1994, NGW) • Yoshi's Island: Super Mario Advance 3 (2002, GBA) • Donkey Kong/Donkey Kong Junior/Mario Bros. (2004, arcade) • Virtual Console (2006-2016, Wii/3DS/Wii U) • Captain Toad: Treasure Tracker (2018, Switch/3DS) • Mario vs. Donkey Kong (2024, Switch)
Tech demos Super Mario 128 (2000, GCN) • New Super Mario Bros. Mii (2011, Wii U)
Mario Kart series Main Super Mario Kart (1992, SNES) • Mario Kart 64 (1996, N64) • Mario Kart: Super Circuit (2001, GBA) • Mario Kart: Double Dash!! (2003, GCN) • Mario Kart DS (2005, DS) • Mario Kart Wii (2008, Wii) • Mario Kart 7 (2011, 3DS) • Mario Kart 8 (2014, Wii U) • Mario Kart Tour (2019, iOS/iPadOS/Android)
Arcade Mario Kart Arcade GP (2005, arcade) • Mario Kart Arcade GP 2 (2007, arcade) • Mario Kart Arcade GP DX (2013, arcade) • Mario Kart Arcade GP VR (2017, arcade)
Other Mario Kart Live: Home Circuit (2020, Switch)
Ports Mario Kart 8 Deluxe (2017, Switch)
Mario Party series Main Mario Party (1998, N64) • Mario Party 2 (1999, N64) • Mario Party 3 (2000, N64) • Mario Party 4 (2002, GCN) • Mario Party 5 (2003, GCN) • Mario Party 6 (2004, GCN) • Mario Party 7 (2005, GCN) • Mario Party 8 (2007, Wii) • Mario Party 9 (2012, Wii) • Mario Party 10 (2015, Wii U) • Super Mario Party (2018, Switch) • Mario Party Superstars (2021, Switch) • Super Mario Party Jamboree (2024, Switch)
Handheld Mario Party Advance (2005, GBA) • Mario Party DS (2007, DS) • Mario Party: Island Tour (2013, 3DS) • Mario Party: Star Rush (2016, 3DS) • Mario Party: The Top 100 (2017, 3DS)
Arcade Super Mario Fushigi no Korokoro Party (2004, arcade) • Super Mario Fushigi no Korokoro Party 2 (2005, arcade) • Mario Party Fushigi no Korokoro Catcher (2009, arcade) • Mario Party Kurukuru Carnival (2012, arcade) • Mario Party Fushigi no Korokoro Catcher 2 (2013, arcade) • Mario Party Challenge World (2016, arcade)
Other Mario Party 4 (2002, Adobe Flash) • Mario Party-e (2003, GBA)
Sports games Mario Golf series Golf (1984, NES) • Stroke & Match Golf (1984, VS. System) • Golf: Japan Course (1987, FDS) • Golf: U.S. Course (1987, FDS) • Golf (1989, GB) • NES Open Tournament Golf (1991, NES) • Mario Golf (1999, N64) • Mario Golf (1999, GBC) • Mobile Golf (2001, GBC) • Mario Golf: Toadstool Tour (2003, GCN) • Mario Golf: Advance Tour (2004, GBA) • Mario Golf: World Tour (2014, 3DS) • Mario Golf: Super Rush (2021, Switch)
Mario Tennis series Mario's Tennis (1995, VB) • Mario Tennis (2000, N64) • Mario Tennis (2000, GBC) • Mario Power Tennis (2004, GCN) • Mario Tennis: Power Tour (2005, GBA) (Bicep Pump [Unknown, Adobe Flash] • Reflex Rally [Unknown, Adobe Flash]) • Mario Tennis Open (2012, 3DS) • Mario Tennis: Ultra Smash (2015, Wii U) • Mario Tennis Aces (2018, Switch)
Super Mario Stadium series Mario Superstar Baseball (2005, GCN) • Mario Super Sluggers (2008, Wii)
Mario Strikers series Super Mario Strikers (2005, GCN) • Mario Strikers Charged (2007, Wii) • Mario Strikers: Battle League (2022, Switch)
Famicom Grand Prix series Famicom Grand Prix: F1 Race (1987, FDS) • Famicom Grand Prix II: 3D Hot Rally (1988, FDS)
Other Donkey Kong Hockey (1984, G&W) • Baseball (1989, GB) • Super Mario Race (1992, GwB) • Easy Racer (1996, SNES) • Mario Hoops 3-on-3 (2006, DS) • Mario Sports Mix (2010, Wii) • Mario Sports Superstars (2017, 3DS) • LEGO Super Mario Goal (2024, Sky Italia)
Canceled games Super Mario Spikers (Wii)
Role-playing games Paper Mario series Paper Mario (2000, N64) • Paper Mario: The Thousand-Year Door (2004, GCN) • Super Paper Mario (2007, Wii) • Paper Mario: Sticker Star (2012, 3DS) • Paper Mario: Color Splash (2016, Wii U) • Paper Mario: The Origami King (2020, Switch)
Mario & Luigi series Mario & Luigi: Superstar Saga (2003, GBA) • Mario & Luigi: Partners in Time (2005, DS) • Mario & Luigi: Bowser's Inside Story (2009, DS) • Mario & Luigi: Dream Team (2013, 3DS) • Mario & Luigi: Paper Jam (2015, 3DS) • Mario & Luigi: Brothership (2024, Switch)
Other Super Mario RPG: Legend of the Seven Stars (1996, SNES)
Remakes Mario & Luigi: Superstar Saga + Bowser's Minions (2017, 3DS) • Mario & Luigi: Bowser's Inside Story + Bowser Jr.'s Journey (2018, 3DS) • Super Mario RPG (2023, Switch) • Paper Mario: The Thousand-Year Door (2024, Switch)
Dr. Mario series Main Dr. Mario (1990, NES/GB) • Dr. Mario 64 (2001, N64) • Dr. Mario Online Rx (2008, WiiWare) • Dr. Mario Express (2008, DSiWare) • Dr. Luigi (2013, Wii U) • Dr. Mario: Miracle Cure (2015, 3DS) • Dr. Mario World (2019, iOS/iPadOS/Android)
Other Dr. Mario (1993, GwB)
Remakes Tetris & Dr. Mario (1994, SNES) • Nintendo Puzzle Collection (2003, GCN) • Dr. Mario & Puzzle League (2005, GBA)
Luigi's Mansion series Main Luigi's Mansion (2001, GCN) • Luigi's Mansion: Dark Moon (2013, 3DS) • Luigi's Mansion 3 (2019, Switch)
Arcade Luigi's Mansion Arcade (2015, arcade)
Remakes Luigi's Mansion (2018, 3DS) • Luigi's Mansion 2 HD (2024, Switch)
Educational games Mario Discovery Series Mario is Missing! (1992, MS-DOS) • Mario is Missing! (1993, SNES) • Mario is Missing! (1993, NES) • Mario's Time Machine (1993, MS-DOS) • Mario's Time Machine (1993, SNES) • Mario's Time Machine (1994, NES) • Mario's Early Years! Fun with Letters (1993, MS-DOS/SNES) • Mario's Early Years! Fun with Numbers (1994, MS-DOS/SNES) • Mario's Early Years! Preschool Fun (1994, MS-DOS/SNES)
Mario Teaches Typing series Mario Teaches Typing (1991, MS-DOS) • Mario Teaches Typing 2 (1996, MS-DOS)
Other Family BASIC (1984, FC) • Super Mario Bros. & Friends: When I Grow Up (1991, MS-DOS)
Ports Mario's Early Years! CD-ROM Collection (1995, MS-DOS)
Art utilities Mario Artist series Mario Artist: Paint Studio (1999, N64DD) • Mario Artist: Talent Studio (2000, N64DD) • Mario Artist: Communication Kit (2000, N64DD) • Mario Artist: Polygon Studio (2000, N64DD)
Other I am a teacher: Super Mario Sweater (1986, FDS) • Super Mario Bros. Print World (1991, MS-DOS) • Mario Paint (1992, SNES) • Super Mario Collection Screen Saver (1997, PC) • Mario no Photopi (1998, N64) • Mario Family (2001, GBC)
Miscellaneous Picross series Mario's Picross (1995, GB) • Mario's Super Picross (1995, SFC) • Picross 2 (1996, GB) • Picross NP Vol. 6 (2000, SFC)
LCD handhelds Mario's Bombs Away (1983, G&W) • Mario's Egg Catch (1990, SMBW) • Luigi's Hammer Toss (1990, SMBW) • Princess Toadstool's Castle Run (1990, SMBW) • Mario the Juggler (1991, G&W)
Pinball Pinball (1984, NES) • Super Mario Bros. (1992, arcade) • Super Mario Bros. Mushroom World (1992, arcade) • Mario Pinball Land (2004, GBA)
Arcade Mario Roulette (1991, arcade) • Piccadilly Circus: Super Mario Bros. 3 (1991, arcade) • Mario World (1991, arcade) • Terebi Denwa: Super Mario World (1992, arcade) • Super Mario World Popcorn (1992, arcade) • Pika Pika Mario (1992, arcade) • Janken Fukubiki: Super Mario World (1992, arcade) • Koopa Taiji (1993, arcade) • Būbū Mario (1993, arcade) • Mario Undōkai (1993, arcade) • Super Mario World (1993, arcade) • Super Mario Kart: Doki Doki Race (1994, arcade) • Mario Bowl (1995, arcade) • Super Mario Attack (1996, arcade) • Super Donkey Kong 2 Swanky no Bonus Slot (1996, arcade) • Donkey Kong (1996, arcade) • Mario Kart 64 (1996, arcade) • Super Mario 64 (1997, arcade) • Super Mario Bros. 3 (Unknown, arcade) • Super Mario World (Unknown, arcade) • Guru Guru Mario (Unknown, arcade) • Dokidoki Mario Chance! (2003, arcade) • Super Mario Fushigi no Janjan Land (2003, arcade) • New Super Mario Bros. Wii Coin World (2011, arcade)
Browser Mario Net Quest (1997, Adobe Shockwave) • Mario's Memory Madness (1998, Adobe Shockwave) • Crazy Counting (1999, Adobe Shockwave) • Dinky Rinky (1999, Adobe Shockwave) • Goodness Rakes (1999, Adobe Shockwave) • Melon Mayhem (1999, Adobe Shockwave) • Nomiss (1999, Adobe Shockwave) • Wario's Whack Attack (1998, Adobe Shockwave) • The Lab (The Bookshelf • The Drafting Table • PolterCue • Ask Madame Clairvoya) (2001, Adobe Flash) • Mario Trivia (Unknown, Adobe Flash) • Mario Memory (Unknown, Adobe Flash) • Virus Attack! (Unknown, Adobe Flash) • Mini-Mario Factory Game! (2004, Adobe Flash) • Bill Bounce (2004, Adobe Flash) • Mario Party 7 Bon Voyage Quiz (2005, Adobe Flash) • Super Mario Strikers (2005, Adobe Flash) • Dr. Mario Vitamin Toss (2005, Adobe Flash) • Bowser's Lair Hockey (2005, Adobe Flash) • Heads-Up (2005, Adobe Flash) • Parasol Fall (2005, Adobe Flash) • Dribble Skillz (2006, Adobe Flash) • Superstar Shootout (2006, Adobe Flash) • Cannon Kaos (2006, Adobe Flash) • 1-Up Hunt! (2006, Adobe Flash) • Super Paper Mario Memory Match (2007, Adobe Flash) • Are You Smarter Than Mario? (2008, Adobe Flash) • Play Nintendo activities (2014–present)
DSiWare applications Mario Calculator (2009, DSiWare) • Mario Clock (2009, DSiWare)
Other games Alleyway (1989, GB) • Yoshi's Safari (1993, SNES) • UNDAKE30 Same Game (1995, SFC) • Mario's Game Gallery (1995, MS-DOS) • Mario's FUNdamentals (1998, Windows) • Yakuman DS (2005, DS)
Tech demos NDDEMO (2001, GCN) • Mario's Face (Unknown, DS)
Crossovers Game & Watch Gallery series Game & Watch Gallery (1997, GB) • Game & Watch Gallery 2 (1997, GB) • Game & Watch Gallery 3 (1999, GBC) • Game & Watch Gallery 4 (2002, GBA)
Super Smash Bros. series Super Smash Bros. (1999, N64) • Super Smash Bros. Melee (2001, GCN) • Super Smash Bros. Brawl (2008, Wii) • Super Smash Bros. for Nintendo 3DS (2014, 3DS) • Super Smash Bros. for Wii U (2014, Wii U) • Super Smash Bros. Ultimate (2018, Switch)
Itadaki Street series Itadaki Street DS (2007, DS) • Fortune Street (2011, Wii)
Mario & Sonic series Mario & Sonic at the Olympic Games (2007, Wii) • Mario & Sonic at the Olympic Games (2008, DS) • Mario & Sonic at the Olympic Winter Games (2009, Wii) • Mario & Sonic at the Olympic Winter Games (2009, DS) • Mario & Sonic at the London 2012 Olympic Games (2011, Wii) • Mario & Sonic at the London 2012 Olympic Games (2012, 3DS) • Mario & Sonic at the Sochi 2014 Olympic Winter Games (2013, Wii U) • Mario & Sonic at the Rio 2016 Olympic Games (2016, Wii U) • Mario & Sonic at the Rio 2016 Olympic Games (2016, 3DS) • Mario & Sonic at the Rio 2016 Olympic Games Arcade Edition (2016, arcade) • Mario & Sonic at the Olympic Games Tokyo 2020 (2019, Switch) • Mario & Sonic at the Olympic Games Tokyo 2020 - Arcade Edition (2020, arcade)
NES Remix series Main NES Remix (2013, Wii U) • NES Remix 2 (2014, Wii U)
Reissues NES Remix Pack (2014, Wii U) • Ultimate NES Remix (2014, 3DS)
Mario + Rabbids series Mario + Rabbids Kingdom Battle (2017, Switch) • Mario + Rabbids Sparks of Hope (2022, Switch)
Other Excitebike: Bun Bun Mario Battle (1997, SNES) • NBA Street V3 (2005, GCN) • Dance Dance Revolution: Mario Mix (2005, GCN) • SSX on Tour (2005, GCN) • Tetris DS (2006, DS) • Captain Rainbow (2008, Wii) • Art Style: PiCTOBiTS (2009, DSiWare) • Nintendo Land (2012, Wii U) • Puzzle & Dragons: Super Mario Bros. Edition (2015, 3DS) • Nintendo World Championships: NES Edition (2024, Switch)
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