Invisible Wario
Invisible Wario is just one of Wario's many, many transformations in the Wario Land series of games. When hit by a certain potion thrown by Mad Scienstein, he turns completely invisible, even to the player. The only way to figure out where he is the occasional cloud of dust by his feet, or the scrolling of the screen as he walks. He also occasionally blinks visible for a few milliseconds, but this has no effect on gameplay other than helping the player locate Wario better. However, it is needed to pass usually protected doors guarded by large eyeballs, as Wario cannot be seen. This is one of the only cases where in-game invisibility is a hindrance to the player, instead of a useful ability. Wario can revert back to normal by going through pipes.